Jean M.N. Feugang

Jean M.N. Feugang

Assistant Research Professor

Reproductive Biology

Department:  Wise Center, Rm 4025


Phone:   (662) 325-7567

Mailing Address:
Mailstop 9815
Mississippi State, MS 39762


    • Post-Doctoral, Univeristy of Arizona
    • Post-Doctoral, Mississippi State University
    • Ph.D., Catholic University of louvain-la-Neuve, Belgium
    • M.S., University of Montpelier and National Institute for Agricultural Research, France
    • B.S., University Henri-Poincare, France

Society Memberships

    • European Association of Embryo Transfer
    • American Society of Animal Science
    • International Embryo Transfer Society
    • Society for the Study of Reproduction


    • Biology of mammalian gametes and embryos
    • Post-collection semen manipulation (i.e., in vitro analyses, purification, and cryopreservation)
    • Non-invasive luminescence and fluorescence bioimaging
    • Nanotechnology in animal production, reproduction, and disease prevention
    • Various biological techniques are employed:
      1. cell and embryo culture;
      2. biochemical and cellular assays (i.e., ELISA and apoptosis analyses);
      3. proteomics (protein isolation, western-blot, and high-throughput approach);
      4. transcriptomics (DNA/RNA isolation, PCR, and high-throughput approach);
      5. and
      6. Biophotonic imaging (bioluminescence and fluorescence).

Selected Publications
  • Aguiar, F.L.N., G.D.A. Gastal, G.M. Ishak, M.O. Gastal, D.I.A. Teixeira, J.R. Figueiredo, E.L. Gastal, J.M. Feugang. 2017. Effects of FSH addition to an enriched medium containing insulin and EGF after long -term culture on functionality of equine ovarian biopsy tissue. Theriogenology 99 (2017) 124-133. Download
  • Durfey, C. L., D. D. Burnet, S. F. Liao, C. S. Steadman, M. A. Crenshaw, H. J. Clemente, S. T. Willard, P. L. Ryan, J. M. Feugang. 2017. Nanotechnology-based selection of boar spermatozoa: growth development and health assessments of produced offspring. Livestock Sciences 205: 137-142. Download
  • Feugang, J.M. 2017. Novel agents for sperm purification, sorting and imaging. Molecular Reproduction Development. Download
  • Gastal, G. D. A., A. Hamilton, B. G. Alves, S. G. S. de Tarso, J. M. Feugang, G. A. Apgar, C. K. Nielsen, E. L. Gastal, W. J. Banz. 2017. Ovarian features in white-tailed deer (Odocoileus virginianus) fawns and does. PLOS ONE. 12(5):30177357. Download
  • Gastal, G. D. A., B. G. Alves, K. A. Alves, M. E. M. Souza, A. D. Vieira, A. S. Varela Jr., J. R. Figueiredo, J. M. Feugang, T. Lucia Jr., E. L. Gastal. 2017. Ovarian fragment sizes affect viability and morphology of preantral follicles during storage at 4°C. Reproduction 153:577-587. Download
  • Gastal, G.D.A., F.L.N. Aguiar, B.G. Alves, K.A. Alves, S.G.S. de Tarso, G.M. Ishak, C.A. Cavinder, J.M. Feugang, E.L. Gastal. 2017. Equine ovarian tissue viability after cryopreservation and in vitro Culture. Theriogenology 97:139-147. Download
  • Wang, T., J. M. Feugang, M. A. Crenshaw, N. Regmi, J. R. Blanton Jr., S. F. Liao. 2017. A systems biology approach using transcriptomic data reveals genes and pathways in porcine skeletal muscle affected by dietary lysine. International Journal of Molecular Sciences 18:885. Download
  • Vasquez, E. S., S. T. Willard, P. L. Ryan, J. M. Feugang, K. B. Walters. 2016. Bioluminescence luciferase-magnetic-nanoparticles as potential imaging agents for mammalian spermatozoa tracking and detection. Journal of Nanobiotechnology 14:20. Download
  • Feugang J. M., J. C. Rodriguez-Munoz, M. A. Crenshaw, S. T. Willard, P. L. Ryan. 2015. Beneficial effects of relaxin on general motility of stored boar spermatozoa. Reproductive Biology and Endocrinology 13:24. Download
  • Feugang J. M., J. M. Greene, H. L. Sanchez-Rodriguez, J. V. Stokes, M. A. Crenshaw, S. T. Willard, P. L. Ryan. 2015. Profiling of relaxin and its receptor proteins in boar reproductive tissues and spermatozoa. Reproductive Biology and Endocrinology 13:46. Download
  • Feugang, J. M., R. C. Youngblood, J. M. Greene, S. T. Willard, P. L. Ryan. 2015. Self-illuminating quantum dots for non-invasive bioluminescence and fluorescence imaging of mammalian gametes. Journal of Nanobiotechnology 13:38. Download
  • Feugang, J. M., S. F. Liao, M. A. Crenshaw, H. Clemente, S. T. Willard, and P. L. Ryan. 2015. Lectin-functionalized magnetic iron oxide nanoparticles for reproductive improvement. Journal of Fertilization: In Vitro - IVF-Worldwide, Reproductive Medicine, Genetics & Stem Cell Biology 3(2):145 (1-5).
  • Feugang, J.M., R.C. Youngblood, S.T. Willard, P.L. Ryan. 2014. Potential use of conjugated quantum dot nanoparticles for bio-labelling of mammalian gametes. Reproduction, Fertility and Development 26(1):187. Download
  • Youngblood, R.C., M. McGee, J.M. Feugang, S.T. Willard, P.L. Ryan. 2014. The use of a whole animal biophotonic model as a screen for the angiogenic potential of estrogenic compounds. International Journal of Medical Sciences 11(6):545-553. Download
  • Greene, J., J.M. Feugang, K.E. Pfeiffer, J.V. Stokes, S.D. Bowers, and P.L. Ryan. 2013. L-arginine enhances cellproliferation and reduces apoptosis in human endometrial RL95-2 cells. Reproductive Biology and Endocrinology Vol. 11:15. Download
  • Feugang, J.M., R.C. Youngblood, J. Greene, A. Fahad, W. Monroe, S.T. Willard, P.L. Ryan. 2012. Application of quantum dot nanoparticles for potential non-invasive bio-imaging of mammalian spermatozoa. Journal of Nanobiotechnology Vol. 10:45. Download
  • Feugang, J.M., S.T. Willard, and P.L. Ryan. 2012. Manipulation of mammalian gametes and embryos: What are we learning from animal settings. Journal of Fertilization: In Vitro 2:e114. Download
  • Greene, J. M., C. W. Dunaway, S. D. Bowers, B. J. Rude, J. M. Feugang, and P. L. Ryan. 2012. Dietary L-arginine supplementation during mouse gestation enhances reproductive performance and Vegfr2 transcription activity in the fetoplacental unit. Journal of Nutrition 142:456-460. Download
  • Borazjani, A., B. Weed, S.H. Elder, J. Feugang, D.L. Christiansen, P.L. Ryan, J. Liao, S. Patnaik. 2011. A comparative biomechanical analysis of term fetal membranes in human and domestic species. American Journal of Obstetrics and Gynecology 365:25-36. Download
  • Feugang, J., S.T. Willard, P.L. Ryan, J. Greene. 2011. In vitro effects of relaxin on gene expression in procine cumulus-oocyte complexes and developing embryos. Reproductive Biology and Endocrinology 9:1:15. Download
  • Feugang, J.M., J.C. Rodriguez-Munoz, S.T. Willard, R. Bathgate, P.L. Ryan. 2011. Examination of relaxin and its receptors expression in pig gametes and embryos. Reproductive Biology and Endocrinology 9:1:10. Download
  • Greene, J., C. Dunaway, S.D. Bowers, B.J. Rude, J.M. Feugang, P.L. Ryan. 2011. In vivo monitoring of fetoplacental Vegfr2 gene activity in a murine pregnancy model using a Vegfr2-luc reporter gene and bioluminescent imaging. Reproductive Biology and Endocrinology 9:51. Download
  • Feugang, J.M., N. Rodriguez-Osorio, A. Kaya, H. Wang, G. Page, G.C. Ostermeier, E.K. Topper, E. Memili. 2010. Transcriptomic landscape of bull spermatozoa: implications for male fertiliy. Reproductive BioMedicine Online 21(3):312-324. Download
  • Feugang, J., A. Kaya, G. Page, L. Chen, T. Mehta, K. Hirani, L. Nazareth, R. Gibbs, E. Memili. 2009. Two-stage genome-wide association study identifies integrin beta 5 as having potential role in bull fertility. BMC Genomics 10:176. Download
  • Feugang, J.M., O.D. Camargo-Rodriguez, E. Memili. 2009. Culture systems for bovine embryos. Livestock Science 121(2-3):141-149. Download
  • Wang, H., N. Rodriguez-Osorio, J.M. Feugang, S. Jung, K. Garrison, C. Wolgemuth, L. Greer, M. Crenshaw, E. Memili. 2009. Effects of culture media and inhibitors on biology of porcine early embryonic development in vitro. Livestock Science 121:102-107. Download
  • Peddinti, D., B. Nanduri, A. Kaya, J.M. Feugang, S.C. Burgess, E. Memili. 2008. Comprehensive proteomic analysis of bovine spermatozoa of varying fertility rates and identification of biomarkers associated with fertility. BMC Systems Biology 2:19. Download
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